Structure of PDB 4jcj Chain B

Receptor sequence
>4jcjB (length=148) Species: 10090 (Mus musculus) [Search protein sequence]
LISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRD
GKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSR
QLIPGDEFALREDGLFCRADHDVVVMVVGEPTLMGDEDERLITRLENT
3D structure
PDB4jcj A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions.
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B C107 C110 C129 D132 C95 C98 C117 D120
BS02 ZN B C17 C20 H39 C42 C5 C8 H27 C30
BS03 ZN B C45 C48 C67 D70 C33 C36 C55 D58
BS04 ZN B C79 C82 H101 C104 C67 C70 H89 C92
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048665 neuron fate specification

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:4jcj, PDBe:4jcj, PDBj:4jcj
PDBsum4jcj
PubMed23750000
UniProtP61372;
P70662|LDB1_MOUSE LIM domain-binding protein 1 (Gene Name=Ldb1)

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