Structure of PDB 4jc0 Chain B

Receptor sequence
>4jc0B (length=421) Species: 2336 (Thermotoga maritima) [Search protein sequence]
VGIKVLGCPKNEADCEVLAGVLREGGHEIVFDVKDADVVVLDTCAFIEDA
KRESIDEIFSFVDAKDQYGYKLVVKGCLVQRYYEELKKEIPEVDQWIGVA
DPEEIANAIETDLVPDRYRKRIDLEERPYAYVKISDGCDRGCTFCSIPSF
KGSLRSRSIEDITREVEDLLKEGKKEIILVAQDTTSYGIDLYRKQALPDL
LRRLNSLNGEFWIRVMYLHPDHLTEEIISAMLELDKVVKYFDVPVQHGSD
KILKLMGRTKSSEELKKMLSSIRERFPDAVLRTSIIVGFPGETEEDFEEL
KQFVEEIQFDKLGAFVYSDEEGTVAFNLKEKVDPEMAKRRQEELLLLQAE
ISNSRLDRFVGKKLKFLVEGKEGKFLVGRTWTEAPEVDGVVFVRGKGKIG
DFLEVVIKEHDEYDMWGSVIL
3D structure
PDB4jc0 Two Fe-S clusters catalyze sulfur insertion by radical-SAM methylthiotransferases.
ChainB
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.4.4: [ribosomal protein uS12] (aspartate(89)-C(3))-methylthiotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FS5 B G9 C10 K12 N13 C46 C79 C148 R150 C152 C155 I157 K161 Q192 G7 C8 K10 N11 C44 C77 C138 R140 C142 C145 I147 K151 Q182
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0035596 methylthiotransferase activity
GO:0035599 aspartic acid methylthiotransferase activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0103039 protein methylthiotransferase activity
Biological Process
GO:0006400 tRNA modification
GO:0018339 peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4jc0, PDBe:4jc0, PDBj:4jc0
PDBsum4jc0
PubMed23542644
UniProtQ9X2H6|RIMO_THEMA Ribosomal protein uS12 methylthiotransferase RimO (Gene Name=rimO)

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