Structure of PDB 4j7q Chain B

Receptor sequence
>4j7qB (length=322) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
KNLINIDKPIKELPASIAIPKEKPLTGEQQKMYDEVLKHFSNPDLKVYTS
EKNKSEDDLKPLEEEEKAWLTRECFLRYLRATKWVLKDCIDRITMTLAWR
REFGISHLGEEHGDKITADLVAVENESGKQVILGYENDARPILYLKPGRQ
NTKTSHRQVQHLVFMLERVIDFMPAGQDSLALLIDFKDYPDVPKVPGGVG
KEVLHILQTHYPERLGKALLTNIPWLAWTFLKLIHPFIDPLTREKLVFDE
PFVKYVPKNELDSLYGGDLKFKYNHDVYWPALVETAREKRDHYFKRFQSF
GGIVGLSEVDLRGTHEKLLYPV
3D structure
PDB4j7q Structural determinants for phosphatidylinositol recognition by Sfh3 and substrate-induced dimer-monomer transition during lipid transfer cycles.
ChainB
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 B7N B W247 F252 W225 F230
BS02 B7N B L160 Q173 V174 L195 L197 F201 L229 Y233 E235 R236 L237 K267 L145 Q158 V159 L180 L182 F186 L207 Y211 E213 R214 L215 K245
Gene Ontology
Molecular Function
GO:0008526 phosphatidylinositol transfer activity
GO:0032934 sterol binding
GO:0042802 identical protein binding
Biological Process
GO:0006869 lipid transport
GO:0008654 phospholipid biosynthetic process
GO:0009410 response to xenobiotic stimulus
GO:0015914 phospholipid transport
GO:0016126 sterol biosynthetic process
GO:0043942 negative regulation of sexual sporulation resulting in formation of a cellular spore
GO:0120009 intermembrane lipid transfer
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005811 lipid droplet
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0071561 nucleus-vacuole junction
GO:0071944 cell periphery
GO:1902556 phosphatidylinositol transporter complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4j7q, PDBe:4j7q, PDBj:4j7q
PDBsum4j7q
PubMed23603387
UniProtP53860|PDR16_YEAST Phosphatidylinositol transfer protein PDR16 (Gene Name=PDR16)

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