Structure of PDB 4j19 Chain B

Receptor sequence
>4j19B (length=76) Species: 9606 (Homo sapiens) [Search protein sequence]
RRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLS
DLERVTSLKVYNWFANRRKEIKRRAN
3D structure
PDB4j19 HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment.
ChainB
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R267 R271 Y291 R297 Y327 K335 R1 R5 Y25 R31 Y61 K69
BS02 dna B R267 R271 F272 W274 K325 N332 R1 R5 F6 W8 K59 N66
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003691 double-stranded telomeric DNA binding

View graph for
Molecular Function
External links
PDB RCSB:4j19, PDBe:4j19, PDBj:4j19
PDBsum4j19
PubMed23685356
UniProtQ6NT76|HMBX1_HUMAN Homeobox-containing protein 1 (Gene Name=HMBOX1)

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