Structure of PDB 4j0m Chain B

Receptor sequence
>4j0mB (length=724) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
DFNETALLLAFKQNSVKSDPNNVLGNWKYEGSCSWRGVSCSDDGRIVGLD
LRNSGLTGTLNLVNLTALPNLQNLYLQGNYFSSGGDSSGSDCYLQVLDLS
SNSISDYSMVDYVFSKCSNLVSVNISNNKLVGKLGFAPSSLQSLTTVDLS
YNILSDKIPESFISDFPASLKYLDLTHNNLSGDFSDLSFGICGNLTFFSL
SQNNLSGDKFPITLPNCKFLETLNISRNNLAGKIPNGEYWGSFQNLKQLS
LAHNRLSGEIPPELSLLCKTLVILDLSGNTFSGELPSQFTACVWLQNLNL
GNNYLSGDFLNTVVSKITGITYLYVAYNNISGSVPISLTNCSNLRVLDLS
SNGFTGNVPSGFCSLQSSPVLEKILIANNYLSGTVPMELGKCKSLKTIDL
SFNELTGPIPKEIWMLPNLSDLVMWANNLTGTIPEGVCVKGGNLETLILN
NNLLTGSIPESISRCTNMIWISLSSNRLTGKIPSGIGNLSKLAILQLGNN
SLSGNVPRQLGNCKSLIWLDLNSNNLTGDLPGELASQAGLVMPGSVSGKQ
FAFVRNEGGTDCRGAGGLVEFEGIRAERLERLPMVHSCPATRIYSGMTMY
TFSANGSMIYFDISYNAVSGFIPPGYGNMGYLQVLNLGHNRITGTIPDSF
GGLKAIGVLDLSHNNLQGYLPGSLGSLSFLSDLDVSNNNLTGPIPFGGQL
TTFPVSRYANNSGLCGVPLRPCGS
3D structure
PDB4j0m Structural basis for differential recognition of brassinolide by its receptors
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MAN B H286 D308 S310 H253 D275 S277
BS02 BLD B W551 F584 F586 R588 Y627 T631 M632 W518 F551 F553 R555 Y594 T598 M599 MOAD: Kd=3.6nM
External links
PDB RCSB:4j0m, PDBe:4j0m, PDBj:4j0m
PDBsum4j0m
PubMed23709366
UniProtQ9ZWC8|BRL1_ARATH Serine/threonine-protein kinase BRI1-like 1 (Gene Name=BRL1)

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