Structure of PDB 4ivy Chain B

Receptor sequence
>4ivyB (length=232) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRH
MSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB4ivy Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
ChainB
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 V376 E380 D538 L539 E542 M543 I54 K58 V72 E76 D222 L223 E226 M227
BS02 1GT B E353 L387 M388 L391 R394 M421 G521 E49 L83 M84 L87 R90 M112 G205
External links
PDB RCSB:4ivy, PDBe:4ivy, PDBj:4ivy
PDBsum4ivy
PubMed23524984
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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