Structure of PDB 4iv2 Chain B

Receptor sequence
>4iv2B (length=238) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLI
LSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB4iv2 Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
ChainB
Resolution2.14 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 V376 E380 D538 L539 E542 I54 K58 L68 V72 E76 D228 L229 E232
BS02 1GR B E353 L387 M388 L391 F404 M421 G521 L525 E49 L83 M84 L87 F100 M115 G211 L215
External links
PDB RCSB:4iv2, PDBe:4iv2, PDBj:4iv2
PDBsum4iv2
PubMed23524984
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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