Structure of PDB 4iui Chain B

Receptor sequence
>4iuiB (length=221) Species: 9606 (Homo sapiens) [Search protein sequence]
LSLTADQMVSALLDAEPPILYSEYDPTRASMMGLLTNLADRELVHMINWA
KRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLD
RMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTEEKDHIHRV
LDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM
KCKNVVPLSDLLLEMLDAHRL
3D structure
PDB4iui Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 V376 L379 E542 M543 I47 K51 L61 V65 L68 E214 M215
BS02 1GQ B M343 L346 E353 L387 M388 L391 M421 I424 F425 G521 M32 L35 E42 L76 M77 L80 M102 I105 F106 G193
External links
PDB RCSB:4iui, PDBe:4iui, PDBj:4iui
PDBsum4iui
PubMed23524984
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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