Structure of PDB 4ire Chain B

Receptor sequence
>4ireB (length=313) Species: 251221 (Gloeobacter violaceus PCC 7421) [Search protein sequence]
MVSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLA
FDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVNISVSPDGTVQYL
ERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKND
DVFLTGWDIESFTAVVKPANFALQNRLESKLDYQLRISRQYFSYIPNIIL
PMLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNLPKTPYMT
YTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVF
LLANIILAFLFFG
3D structure
PDB4ire Signal transduction pathways in the pentameric ligand-gated ion channels.
ChainB
Resolution3.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LMD B K33 T244 K30 T241
BS02 OXL B R293 R296 R290 R293
BS03 OXL B Y221 E222 H277 Y218 E219 H274
BS04 LMD B D31 D32 I233 I236 A237 L241 N245 D28 D29 I230 I233 A234 L238 N242
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:4ire, PDBe:4ire, PDBj:4ire
PDBsum4ire
PubMed23667707
UniProtQ7NDN8|GLIC_GLOVI Proton-gated ion channel (Gene Name=glvI)

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