Structure of PDB 4ibi Chain B

Receptor sequence
>4ibiB (length=127) Species: 128952 (Ebola virus - Mayinga, Zaire, 1976) [Search protein sequence]
MGKPDISAKDLRNIMYDHLPGFGTAFHQLVQVICKLGKDSNSLDIIHAEF
QASLAEGDSPQCALIQITKRVPIFQDAAPPVIHIRSRGDIPRACQKSLRP
VPPSPKIDRGWVCVFQLQDGKTLGLKI
3D structure
PDB4ibi In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity.
ChainB
Resolution1.473 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1D8 B Q241 Q244 K248 K251 P293 I295 D302 F328 Q28 Q31 K35 K38 P80 I82 D89 F115 MOAD: Kd=73uM
External links
PDB RCSB:4ibi, PDBe:4ibi, PDBj:4ibi
PDBsum4ibi
PubMed24495995
UniProtQ05127|VP35_EBOZM Polymerase cofactor VP35 (Gene Name=VP35)

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