Structure of PDB 4ibg Chain B

Receptor sequence
>4ibgB (length=123) Species: 128952 (Ebola virus - Mayinga, Zaire, 1976) [Search protein sequence]
DISAKDLRNIMYDHLPGFGTAFHQLVQVICKLGKDSNSLDIIHAEFQASL
AEGDSPQCALIQITKRVPIFQDAAPPVIHIRSRGDIPRACQKSLRPVPPS
PKIDRGWVCVFQLQDGKTLGLKI
3D structure
PDB4ibg In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity.
ChainB
Resolution1.413 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 1D6 B Q241 V245 K248 K251 P293 I295 Q24 V28 K31 K34 P76 I78 MOAD: Kd=108uM
PDBbind-CN: -logKd/Ki=3.97,Kd=108.0uM
External links
PDB RCSB:4ibg, PDBe:4ibg, PDBj:4ibg
PDBsum4ibg
PubMed24495995
UniProtQ05127|VP35_EBOZM Polymerase cofactor VP35 (Gene Name=VP35)

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