Structure of PDB 4iae Chain B

Receptor sequence
>4iaeB (length=182) Species: 103690 (Nostoc sp. PCC 7120 = FACHB-418) [Search protein sequence]
MYGLVNKAIQDMISKHHGEDTWEAIKQKAGLEDIDFFVGMEAYSDDVTYH
LVGAASEVLGKPAEELLIAFGEYWVTYTSEEGYGELLASAGDSLPEFMEN
LDNLHARVGLSFPQLRPPAFECQHTSSKSMELHYQSTRAGLAPMVLGLLH
GLGKRFQTKVEVTQTAFRETGEDHDIFSIKYE
3D structure
PDB4iae Insights into BAY 60-2770 Activation and S-Nitrosylation-Dependent Desensitization of Soluble Guanylyl Cyclase via Crystal Structures of Homologous Nostoc H-NOX Domain Complexes.
ChainB
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.6.1.2: guanylate cyclase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1DX B M1 Y2 L4 V5 W74 Y83 F97 L101 H105 V108 F112 L115 R116 P118 Y134 S136 R138 L141 M144 L148 M1 Y2 L4 V5 W74 Y83 F97 L101 H105 V108 F112 L115 R116 P118 Y134 S136 R138 L141 M144 L148
Gene Ontology
Molecular Function
GO:0020037 heme binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4iae, PDBe:4iae, PDBj:4iae
PDBsum4iae
PubMed23614626
UniProtQ8YUQ7

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