Structure of PDB 4i53 Chain B

Receptor sequence
>4i53B (length=335) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
KTTLFCASDAKAYEKEVHNVWATHACVPTDPNPQEMVLANVTENFNMWKN
DMVEQMHEDIISLWDESLKPCVKLTGGSAITQACPKVSFDPIPLHYCAPA
GFAILKCNNKTFNGTGPCRNVSTVQCTHGIKPVVSTQLLLNGSLAEEEII
IRSENLTNNAKTIIVHLNESVNIVCTRPNNIRQAHCNINESKWNNTLQKV
GEELAKHFPSKTIKFEPSSGGDLEITTHSFNCRGEFFYCNTSDLFNGTYR
NGTYNHTGRSSNGTITLQCKIKQIINMWQEVGRAIYAPPIEGEITCNSNI
TGLLLLRDDTETFRPGGGDMRDNWRSELYKYKVVE
3D structure
PDB4i53 Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic Characterization.
ChainB
Resolution2.5002 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1C1 B V255 S256 E370 S375 F376 I424 N425 M426 W427 G431 G473 M475 V134 S135 E224 S229 F230 I275 N276 M277 W278 G282 G318 M320 MOAD: Kd=110nM
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4i53, PDBe:4i53, PDBj:4i53
PDBsum4i53
PubMed23667716
UniProtC6G099

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