Structure of PDB 4i18 Chain B

Receptor sequence

>4i18B (length=215) Species: 10090 (Mus musculus) [Search protein sequence]

SDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIY
SASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQYYSYYYPFT
FGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQ
WKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVT
HQGLSSPVTKSFNRG

3D structure

PDB

4i18 Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling.

Chain

Resolution

3.238 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CA	B	D2 S94 Y95	D2 S94 Y95

External links

PDB	RCSB:4i18, PDBe:4i18, PDBj:4i18
PDBsum	4i18
PubMed	25589173

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