Structure of PDB 4hp8 Chain B

Receptor sequence
>4hp8B (length=246) Species: 176299 (Agrobacterium fabrum str. C58) [Search protein sequence]
KNPFSLEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDII
AKDGGNASALLIDFADPLAAKDSFTDAGFDILVNNAGIIRRADSVEFSEL
DWDEVMDVNLKALFFTTQAFAKELLAKGRSGKVVNIASLLSFQGGIRVPS
YTAAKHGVAGLTKLLANEWAAKGINVNAIAPGYIETNNTEALRADAARNK
AILERIPAGRWGHSEDIAGAAVFLSSAAADYVHGAILNVDGGWLAR
3D structure
PDB4hp8 Crystal structure of a putative 2-deoxy-d-gluconate 3-dehydrogenase from Agrobacterium Tumefaciens (target EFI-506435) with bound NADP
ChainB
Resolution1.35 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G20 S139 V149 Y152 K156
Catalytic site (residue number reindexed from 1) G19 S138 V148 Y151 K155
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP B G16 N18 T19 G20 L21 R41 R42 D64 F65 N86 G88 I89 I137 Y152 K156 P182 G183 I185 T187 N189 T190 G15 N17 T18 G19 L20 R40 R41 D63 F64 N85 G87 I88 I136 Y151 K155 P181 G182 I184 T186 N188 T189
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008678 2-deoxy-D-gluconate 3-dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding

View graph for
Molecular Function
External links
PDB RCSB:4hp8, PDBe:4hp8, PDBj:4hp8
PDBsum4hp8
PubMed
UniProtA9CEQ9

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