Structure of PDB 4hk5 Chain B

Receptor sequence
>4hk5B (length=362) Species: 73501 (Cordyceps militaris) [Search protein sequence]
PVVVDIHTHMYPPSYIAMLEKRQTIPLVPRLILLSSELAALDALPGRPLS
THFASLAQKMHFMDTNGIRVSVISLANPWFDFLAPDEAPGIADAVNAEFS
DMCAQHVGRLFFFAALPLSAPVDAVKASIERVKNLKYCRGIILGTSGLGK
GLDDPHLLPVFEAVADAKLLVFLHPHYGLPNEVYGPRSEEYGHVLPLALG
FPMETTIAVARMYMAGVFDHVRNLQMLLAHSGGTLPFLAGRIESCIVHDG
HLVKTGKVPKDRRTIWTVLKEQIYLDAVIYSEVGLQAAIASSGADRLMFG
TDHPFFPPIEEDVQGPWDSSRLNAQAVIKAVGEGSSDAAAVMGLNAVRVL
SLKAELEHHHHH
3D structure
PDB4hk5 Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.1.66: uracil-5-carboxylate decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B H12 H14 H195 D323 H7 H9 H174 D302
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016831 carboxy-lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0019748 secondary metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4hk5, PDBe:4hk5, PDBj:4hk5
PDBsum4hk5
PubMed23917530
UniProtG3J531

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