Structure of PDB 4hjx Chain B

Receptor sequence
>4hjxB (length=306) Species: 243232 (Methanocaldococcus jannaschii DSM 2661) [Search protein sequence]
MDEFEMIKRNTSEIISEEELREVLKKDEKSARIGFEPSGKIHLGHYLQIK
KMIDLQNAGFDIIIYLADLGAYLNQKGELDEIRKIGDYNKKVFEAMGLKA
KYVYGSENCLDKDYTLNVYRLALKTTLKRARRSMELIAREDENPKVAEVI
YPIMQVNNIHYSGVDVAVGGMEQRKIHMLARELLPKKVVCIHNPVLTGLD
GEGKMSSSKGNFIAVDDSPEEIRAKIKKAYCPAGVVEGNPIMEIAKYFLE
YPLTIKRPEKFGGDLTVNSYEELESLFKNKELHPMDLKNAVAEELIKILE
PIRKRL
3D structure
PDB4hjx A genetically encoded 19F NMR probe for tyrosine phosphorylation.
ChainB
Resolution2.91 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.1: tyrosine--tRNA ligase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 F2Y B R32 G34 E36 Y65 A67 Y151 Q155 N158 Q173 R32 G34 E36 Y65 A67 Y151 Q155 N158 Q173
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004831 tyrosine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006437 tyrosyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:4hjx, PDBe:4hjx, PDBj:4hjx
PDBsum4hjx
PubMed23450644
UniProtQ57834|SYY_METJA Tyrosine--tRNA ligase (Gene Name=tyrS)

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