Structure of PDB 4hec Chain B

Receptor sequence
>4hecB (length=163) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
SMVRYFYDTEFIEDGHTIELISIGVVAEDGREYYAVSTEFDPERAGSWVR
THVLPKLPPPASQLWRSRQQIRLDLEEFLRIDGTDSIELWAWVGAYDHVA
LCQLWGPMTALPPTVPRFTRELRQLWEDRGCPRMPPRPRDVHDALVDARD
QLRRFRLITSTDD
3D structure
PDB4hec Mycobacterium tuberculosis Rv2179c Protein Establishes a New Exoribonuclease Family with Broad Phylogenetic Distribution.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B D7 T8 D96 D8 T9 D97
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
GO:0004532 RNA exonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4hec, PDBe:4hec, PDBj:4hec
PDBsum4hec
PubMed24311791
UniProtP9WJ73|EXRBN_MYCTU 3'-5' exoribonuclease Rv2179c (Gene Name=Rv2179c)

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