Structure of PDB 4han Chain B

Receptor sequence
>4hanB (length=293) Species: 9606 (Homo sapiens) [Search protein sequence]
GSMMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQV
DLQNGSSVKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFK
REKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHS
IGFSFSSHMRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSK
DIALHLNPRLNIKAFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCD
VREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW
3D structure
PDB4han Structural basis for recognition of autophagic receptor NDP52 by the sugar receptor galectin-8.
ChainB
Resolution2.551 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B K204 E268 I270 K279 V280 A281 N283 G284 H286 R315 K180 E244 I246 K255 V256 A257 N259 G260 H262 R291
BS02 NAD B R45 Q47 R59 H65 R69 N79 W86 E89 R47 Q49 R61 H67 R71 N81 W88 E91
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:4han, PDBe:4han, PDBj:4han
PDBsum4han
PubMed23511477
UniProtO00214|LEG8_HUMAN Galectin-8 (Gene Name=LGALS8)

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