Structure of PDB 4h9x Chain B

Receptor sequence
>4h9xB (length=318) Species: 235909 (Geobacillus kaustophilus HTA426) [Search protein sequence]
EMVETVCGPVPVEQLGKTLIHEHFLFGYPGFQGDVTRGTFREDESLRVAV
EAAEKMKRHGIQTVVDPTPNDCGRNPAFLRRVAEETGLNIICATGYYYPP
YFQFRRLLGTAEDDIYDMFMAELTEGIADTGIKAGVIKLASSKGRITEYE
KMFFRAAARAQKETGAVIITHTQEGTMGPEQAAYLLEHGADPKKIVIGHM
CGNTDPDYHRKTLAYGVYIAFDCFGIQGMVGAPTDEERVRTLLALLRDGY
EKQIMLSHNTVNVWLGRPFTLPEPFAEMMKNWHVEHLFVNIIPALKNEGI
RDEVLEQMFIGNPAALFS
3D structure
PDB4h9x Structural evidence of a productive active site architecture for an evolved quorum-quenching GKL lactonase.
ChainB
Resolution2.201 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H23 H25 K145 H178 H206 G209 C230 N266
Catalytic site (residue number reindexed from 1) H21 H23 K138 H171 H199 G202 C223 N259
Enzyme Commision number 3.5.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE B H23 H25 K145 N266 H21 H23 K138 N259
BS02 ZN B K145 H178 H206 K138 H171 H199
BS03 HL4 B H25 Y30 N266 V268 W271 H23 Y28 N259 V261 W264
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0009056 catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4h9x, PDBe:4h9x, PDBj:4h9x
PDBsum4h9x
PubMed23461395
UniProtQ5KZU5

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