Structure of PDB 4h8k Chain B

Receptor sequence
>4h8kB (length=138) Species: 155900 (uncultured organism) [Search protein sequence]
KIIIYTDGGARGNPGPAGIGVVITDEKGNTLHESSAYIGETTNNVAEYEA
LIRALEDLQMFGDKLVDMEVEVRMNSELIVRQMQGVYKVKEPTLKEKFAK
IAHIKMERVPNLVFVHIPREKNARADELVNEAIDKALS
3D structure
PDB4h8k Crystal structure of metagenome-derived LC11-RNase H1 in complex with RNA/DNA hybrid
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna B G11 A12 R13 G14 N15 N45 N77 E79 G9 A10 R11 G12 N13 N43 N75 E77
BS02 dna B N15 T44 N45 N46 L80 Q84 Y89 K90 V91 K92 L96 N13 T42 N43 N44 L78 Q82 Y87 K88 V89 K90 L94
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:4h8k, PDBe:4h8k, PDBj:4h8k
PDBsum4h8k
PubMed23500886
UniProtE0X767

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