Structure of PDB 4gyj Chain B

Receptor sequence
>4gyjB (length=617) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
ASASKRAIDANQIVNRMSLDEKLGQMLMPDFRNWQKEGESSPQALTKMND
EVASLVKKYQFGGIILFAENVKTTKQTVQLTDDYQKASPKIPLMLSIDQE
GGIVTRLGEGTNFPGNMALGAARSRINAYQTGSIIGKELSALGINTDFSP
VVDINNNPDNPVIGVRSFSSNRELTSRLGLYTMKGLQRQDIASALKHFPG
HGDTDVDSHYGLPLVSHGQERLREVELYPFQKAIDAGADMVMTAHVQFPA
FDDTTYKSKLDGSDILVPATLSKKVMTGLLRQEMGFNGVIVTNALNMKAI
ADHFGQEEAVVMAVKAGVDIALMPASVTSLKEEQKFARVIQALKEAVKNG
DIPEQQINNSVERIISLKIKRGMYPARNSDSTKEKIAKAKKIVGSKQHLK
AEKKLAEKAVTVLKNEQHTLPFKPKKGSRILIVAPYEEQTASIEQTIHDL
IKRKKIKPVSLSKMNFASQVFKTEHEKQVKEADYIITGSYVVKNDPVVND
GVIDDTISDSSKWATVFPRAVMKAALQHNKPFVLMSLRNPYDAANFEEAK
ALIAVYGFKGYANGRYLQPNIPAGVMAIFGQAKPKGTLPVDIPSVTKPGN
TLYPLGYGLNIKTGRPL
3D structure
PDB4gyj Active Site Plasticity within the Glycoside Hydrolase NagZ Underlies a Dynamic Mechanism of Substrate Distortion.
ChainB
Resolution1.65 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N318 N524
Catalytic site (residue number reindexed from 1) N293 N499
Enzyme Commision number 3.2.1.52: beta-N-acetylhexosaminidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MUB B S65 S66 S40 S41
BS02 MUB B R57 F92 R131 H234 N321 M322 R32 F67 R106 H209 N296 M297
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004563 beta-N-acetylhexosaminidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0009254 peptidoglycan turnover
GO:0071555 cell wall organization
Cellular Component
GO:0005576 extracellular region
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4gyj, PDBe:4gyj, PDBj:4gyj
PDBsum4gyj
PubMed23177201
UniProtP40406|NAGZ_BACSU Beta-hexosaminidase (Gene Name=nagZ)

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