Structure of PDB 4gy5 Chain B

Receptor sequence
>4gy5B (length=210) Species: 9606 (Homo sapiens) [Search protein sequence]
LYKVNEYVDARDTNMGAWFEAQVVRVTRKEDVIYHVKYDDYPENGVVQMN
SRDVRARARTIIKWQDLEVGQVVMLNYNPDNPKERGFWYDAEISRKRETR
TARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGSPMVDNPMRRKSGP
SCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCPLSSVP
SEDEWYCPEC
3D structure
PDB4gy5 Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein
ChainB
Resolution2.956 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y188 Y191 E193 N194 C316 D328 Q330 M332 P353 E355 D356 Y38 Y41 E43 N44 C166 D178 Q180 M182 P200 E202 D203
BS02 ZN B C302 C305 C313 C316 C152 C155 C163 C166
BS03 ZN B C318 H341 C168 H191
External links
PDB RCSB:4gy5, PDBe:4gy5, PDBj:4gy5
PDBsum4gy5
PubMed23161542
UniProtQ96T88|UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1 (Gene Name=UHRF1)

[Back to BioLiP]