Structure of PDB 4gxw Chain B

Receptor sequence
>4gxwB (length=364) Species: 339670 (Burkholderia ambifaria AMMD) [Search protein sequence]
GTPGNVPAARTGIEITAAHRAFFHALPKVELHCHLLGAVRHDTFVALAQR
SGAPIERAEIDAFYARGEKPVGVLHVLRALDRYLLTRPDDLRRIAYEYLE
DAAAHNVRHAEFFWNPTGTVRVSGIPYADAQAAIVTGMRDAARDFGIGAR
LIPSIDREQDPDEAVAIVDWMKANRADEVAGIGIDYRENDRPPELFWKAY
RDARAAGFRTTAHAGEFGMPWRNVETAVDLLHVDRVDHGYTIVDNPELCA
RYAERGIVFTVVPTNSYYLRTLPPDQWAERHPMRKMPGLGLKIHPNTDDP
TLHKVNPSEAWELMFSHFGFTIADLKQFMLNGIDGAWVDDDTKAAWRAAW
APEFDMLADTLAAD
3D structure
PDB4gxw Crystal structure of a cog1816 amidohydrolase (target EFI-505188) from Burkhoderia ambifaria, with bound Zn
ChainB
Resolution1.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H34 H36 H215 E218 H240 D300
Catalytic site (residue number reindexed from 1) H32 H34 H213 E216 H238 D298
Enzyme Commision number 3.5.4.4: adenosine deaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B H34 H36 H215 D300 H32 H34 H213 D298
Gene Ontology
Molecular Function
GO:0000034 adenine deaminase activity
GO:0004000 adenosine deaminase activity
GO:0016787 hydrolase activity
GO:0019239 deaminase activity
GO:0046872 metal ion binding
GO:0046936 2'-deoxyadenosine deaminase activity
Biological Process
GO:0006146 adenine catabolic process
GO:0043103 hypoxanthine salvage
Cellular Component
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:4gxw, PDBe:4gxw, PDBj:4gxw
PDBsum4gxw
PubMed
UniProtQ0B6Q2

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