Structure of PDB 4gug Chain B

Receptor sequence
>4gugB (length=245) Species: 99287 (Salmonella enterica subsp. enterica serovar Typhimurium str. LT2) [Search protein sequence]
TVTVRDLVVGEGAPKIIVSLMGKTITDVKSEALAYREADFDILEWRVDHF
ANVTTAESVLEAAGAIREIITDKPLLFTFRSAEQALTTGQYIDLNRAAVD
SGLVDMIDLELFTGDDEVKATVGYAHQHNVAVIMSNHDFHKTPAAEEIVQ
RLRKMQELGADIPKIAVMPQTKADVLTLLTATVEMQERYADRPIITMSMS
KTGVISRLAGEVFGSAATFGAVKKASAPGQISVADLRTVLTILHQ
3D structure
PDB4gug Reassessing the type I dehydroquinate dehydratase catalytic triad: Kinetic and structural studies of Glu86 mutants.
ChainB
Resolution1.62 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H143 K170
Catalytic site (residue number reindexed from 1) H137 K164
Enzyme Commision number 4.2.1.10: 3-dehydroquinate dehydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3DS B E46 R48 R82 K170 M203 R213 F225 A233 Q236 E44 R46 R80 K164 M197 R207 F219 A227 Q230
Gene Ontology
Molecular Function
GO:0003855 3-dehydroquinate dehydratase activity
GO:0016829 lyase activity
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
GO:0046279 3,4-dihydroxybenzoate biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4gug, PDBe:4gug, PDBj:4gug
PDBsum4gug
PubMed23341204
UniProtP58687|AROD_SALTY 3-dehydroquinate dehydratase (Gene Name=aroD)

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