Structure of PDB 4giv Chain B

Receptor sequence
>4givB (length=184) Species: 320372,559292 [Search protein sequence]
THINLKVSDSEIFFKIKKTTPLRRLMEAFAKRQGKEMDSLRFLYDGIRIQ
ADQTPEDLDMEDNDIIEAHREQGSTVVTTESGLKYEDLTEGSEARAGQTV
SVHYTGWLTDGQKFGSSKDRNDPFAFVLGGGMVIKGWDEGVQGMKVGGVR
RLTIPPQLGYGARGAGGVIPPNATLVFEVELLDV
3D structure
PDB4giv A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.
ChainB
Resolution2.45 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y33 F43 G44 I63 Y89 F106
Catalytic site (residue number reindexed from 1) Y104 F114 G115 I134 Y160 F177
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4GI B Y33 W66 Y89 I98 Y104 W137 Y160 I169
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006457 protein folding

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4giv, PDBe:4giv, PDBj:4giv
PDBsum4giv
PubMed24366729
UniProtQ12306|SMT3_YEAST Ubiquitin-like protein SMT3 (Gene Name=SMT3);
Q3JK38

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