Structure of PDB 4gdm Chain B

Receptor sequence
>4gdmB (length=258) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
LVPRGSMILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFADYSRLY
VDLPGHGGSAAISVDGFDDVTDLLRKTLVSYNILDFWLVGYSLGGRVAMM
AACQGLAGLCGVIVEGGHPGLQNAEQRAERQRSDRQWVQRFLTEPLTAVF
ADWYQQPVFASLNDDQRRELVALRSNNNGATLAAMLEATSLAVQPDLRAN
LSARTFAFYYLCGERDSKFRALAAELAADCHVIPRAGHNAHRENPAGVIA
SLAQILRF
3D structure
PDB4gdm Crystal Structures of E. coli Native MenH and Two Active Site Mutants.
ChainB
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.99.20: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 B S86 L87 R90 S92 L93 R96
BS02 CL B Y85 Y148 Y91 Y154
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0070205 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity
Biological Process
GO:0009234 menaquinone biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4gdm, PDBe:4gdm, PDBj:4gdm
PDBsum4gdm
PubMed23637813
UniProtP37355|MENH_ECOLI 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (Gene Name=menH)

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