Structure of PDB 4gdj Chain B

Receptor sequence
>4gdjB (length=321) Species: 1129347 (Influenza A virus (A/little yellow-shouldered bat/Guatemala/060/2010(H17N10))) [Search protein sequence]
MCEVKGWVPTHRPGDLILSRRAYVSCDLTSCFKFFIAYGLSEESLYKTPI
GSANTLSTSEMILPGRSSSACFDGLKWTVLVSNGRDRNSFIMIKYGEEIT
DTFSASRGGPLRLPNSECICVEGSCFVLVSDGPNVNQSVHRIYELQNGTV
QRWKQLNTTGINFEYSTCYTINNLIKCTGTNLWNDAKRPLLRFTKDLNYQ
IVEPCNGAPTDFPRGGLTTPSCKMAQEKGEGGIQGFILDEKPAWTSKTKT
ELSQNGFVLEQIPDGIESEGTVSLSYELFSNKRTGRSGFFQPKGECQRVC
FWLEIEIQELSTFCGINSPVQ
3D structure
PDB4gdj Crystal structures of two subtype N10 neuraminidase-like proteins from bat influenza A viruses reveal a diverged putative active site.
ChainB
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y277 T292 Q371 R406
Catalytic site (residue number reindexed from 1) Y165 T180 Q254 R286
Enzyme Commision number 3.2.1.18: exo-alpha-sialidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B N293 D297 D324 G345 G347 N181 D185 D211 G229 G231
Gene Ontology
Molecular Function
GO:0004308 exo-alpha-sialidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0016020 membrane
GO:0033644 host cell membrane
GO:0055036 virion membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4gdj, PDBe:4gdj, PDBj:4gdj
PDBsum4gdj
PubMed23012478
UniProtH6QM95

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