Structure of PDB 4ga6 Chain B

Receptor sequence
>4ga6B (length=493) Species: 69014 (Thermococcus kodakarensis KOD1) [Search protein sequence]
MKAKIRILDMFSGRYTVLINEEDAKEAKLHPDDLVKIEAGKKAVYGSVAL
SNLVGKGEVGISRDVLDLHNFSEGETVSVIPAGTPESVRYIKKKMHGEKL
RKVEIEAIVRDIVDRKLRDIEISSFVTALEINGLDMDEIAALTIAMAETG
DMLDIDRKPIMDVHSIGGVPGNKTNILVVPIVAAAGLTIPKTSSRAITSA
AGTADVVEVFADVSFSLDEIKRIVEKVGACLVWGGALNLAPADDITIKAE
RALSIDPTGLMLASIMSKKYAMGSQYVLIDIPTGKGVKVETVEEARSLAR
DFIELGKRLGQYVEVAITYGGQPIGHTVGPALEAREALSALMTGKGPGSL
IEKATGLAGILLEMGGVAPAGTGKKMAKEILESGKAWEKMKEIIEAQGGD
PNIKPEEIPIGDKTYTFTAATSGYVTAIDNRAITAIARAAGAPEDKGAGI
ELYVKVGEKVKEGDPLFTIHAEHEARLDQAIVLARRTEPIRIE
3D structure
PDB4ga6 Structure analysis of archaeal AMP phosphorylase reveals two unique modes of dimerization
ChainB
Resolution2.21 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D162 V163 H164 S165 T203 D243 A249 S264 K268 K269
Catalytic site (residue number reindexed from 1) D162 V163 H164 S165 T203 D243 A249 S264 K268 K269
Enzyme Commision number 2.4.2.57: AMP phosphorylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP B H164 S165 I166 S194 A196 I197 T198 S199 T203 D256 M261 S264 K288 H164 S165 I166 S194 A196 I197 T198 S199 T203 D256 M261 S264 K288
Gene Ontology
Molecular Function
GO:0004645 1,4-alpha-oligoglucan phosphorylase activity
GO:0016208 AMP binding
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
GO:0042301 phosphate ion binding
Biological Process
GO:0006196 AMP catabolic process
GO:0006206 pyrimidine nucleobase metabolic process
GO:0006213 pyrimidine nucleoside metabolic process
GO:0046125 pyrimidine deoxyribonucleoside metabolic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:4ga6, PDBe:4ga6, PDBj:4ga6
PDBsum4ga6
PubMed23659790
UniProtQ5JCX3|AMPPA_THEKO AMP phosphorylase (Gene Name=deoA)

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