Structure of PDB 4g83 Chain B

Receptor sequence
>4g83B (length=198) Species: 9606 (Homo sapiens) [Search protein sequence]
EFIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQ
IKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPAS
HLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSC
VGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYR
3D structure
PDB4g83 Crystal Structure of p73 DNA-Binding Domain Tetramer bound to a Full Response-Element
ChainB
Resolution4.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B S261 R293 C295 A296 R300 S149 R181 C183 A184 R188
BS02 ZN B H197 C258 C262 H85 C146 C150
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4g83, PDBe:4g83, PDBj:4g83
PDBsum4g83
PubMed
UniProtO15350|P73_HUMAN Tumor protein p73 (Gene Name=TP73)

[Back to BioLiP]