Structure of PDB 4fyh Chain B

Receptor sequence
>4fyhB (length=125) Species: 10116 (Rattus norvegicus) [Search protein sequence]
RRSVYFCGSIRGGREDQALYARIVSRLRRYGKVLTGDQFIHEQNLNWLQQ
ADVVVAEVTQPSLGVGYELGRAVALGKPILCLFRPQSGRVLSAMIRGAAD
GSRFQVWDYAEGEVETMLDRYFEAY
3D structure
PDB4fyh Structure of the oncoprotein Rcl bound to three nucleotide analogues.
ChainB
Resolution2.44 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TR5 B S117 A118 M119 S92 A93 M94 PDBbind-CN: -logKd/Ki=4.85,Ki~14uM
BS02 TR5 B C15 G16 S17 I18 R19 N69 S87 G89 E93 C7 G8 S9 I10 R11 N44 S62 G64 E68 PDBbind-CN: -logKd/Ki=4.85,Ki~14uM
Gene Ontology
Molecular Function
GO:0070694 deoxyribonucleoside 5'-monophosphate N-glycosidase activity
Biological Process
GO:0009159 deoxyribonucleoside monophosphate catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4fyh, PDBe:4fyh, PDBj:4fyh
PDBsum4fyh
PubMed23385460
UniProtO35820|DNPH1_RAT 5-hydroxymethyl-dUMP N-hydrolase (Gene Name=Dnph1)

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