Structure of PDB 4fvv Chain B

Receptor sequence
>4fvvB (length=415) Species: 1491 (Clostridium botulinum) [Search protein sequence]
SINDSKILSLQNKKNTLMDTSGYNAEVRVEGNVQLNPIFPFDFKLGSSGD
DRGKVIVTQNENIVYNAMYESFSISFWIRINKWVSNLPGYTIIDSVKNNS
GWSIGIISNFLVFTLKQNENSEQDINFSYDISKNAAGYNKWFFVTITTNM
MGNMMIYINGKLIDTIKVKLTGINFSKTITFQMNKIPNTGSDNINMWIRD
FYIFAKELDDKDINILFNSLQYTNVVKDYWGNDLRYDKEYYMINVNYMNR
YMSKKGNGIVFNTRKNNNDFNEGYKIIIKRIRGNTNDTRVRGENVLYFNT
TIDNKQYSLGMYKPSRNLGTDLVPLGALDQPMDEIRKYGSFIIQPCNTFD
YYASQLFLSSNATTNRLGILSIGSYSFRLGGDWYRHEYLIPVIKIEHYAS
LLESTSTHWVFVPAS
3D structure
PDB4fvv Botulinum neurotoxin serotype C associates with dual ganglioside receptors to facilitate cell entry.
ChainB
Resolution2.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K906 I969
Catalytic site (residue number reindexed from 1) K44 I107
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA B Y1115 I1240 G1241 S1242 S1274 Y247 I372 G373 S374 S406
Gene Ontology
Cellular Component
GO:0005576 extracellular region

View graph for
Cellular Component
External links
PDB RCSB:4fvv, PDBe:4fvv, PDBj:4fvv
PDBsum4fvv
PubMed23027864
UniProtQ9LBR1

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