Structure of PDB 4fpv Chain B

Receptor sequence
>4fpvB (length=257) Species: 7955 (Danio rerio) [Search protein sequence]
TAKSEVEDSKLSIISWNVDGLDTLNLADRARGLCSYLALYTPDVVFLQEL
IPAYVQYLKKRAVSYLFFEGSDDGYFTGIMLRKSRVKFLESEIICFPTTQ
MMRNLLIAQVTFSGQKLYLMTSHLESCKNQSQERTKQLRVVLQKIKEAPE
DAIVIFAGDTNLRDAEVANVGGLPAGVCDVWEQLGKQEHCRYTWDTKANS
NKTVPYVSRCRFDRIFLRSAKTAPPVTPDHMALIGMEKLDCGRYTSDHWG
IYCTFNT
3D structure
PDB4fpv Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.
ChainB
Resolution1.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.4.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B K240 N241 Q244 K128 N129 Q132
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:4fpv, PDBe:4fpv, PDBj:4fpv
PDBsum4fpv
PubMed23104058
UniProtQ5XJA0|TYDP2_DANRE Tyrosyl-DNA phosphodiesterase 2 (Gene Name=tdp2)

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