Structure of PDB 4fes Chain B

Receptor sequence
>4fesB (length=425) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
MDPSQYASSSSWTSFLKSIASFNGDLSSLSAPPFILSPISLTEFSQYWAE
HPELFLEPSFINDDNYKEHCLIDPEVESPELARMLAVTKWFISTLKSQYC
SRNESLGSEKKPLNPFLGELFVGKWENKEHPEFGETVLLSEQVSHHPPVT
AFSIFNDKNKVKLQGYNQIKASFTKSLMLTVKQFGHTMLDIKDESYLVTP
PPLHIEGILVASPFVELEGKSYIQSSTGLLCVIEFSGKKNSFKARIYKDS
KDSKDKEKALYTISGQWSGSSKIIKASRLFYDAARIPAEHLNVKPLEEQH
PLESRKAWYDVAGAIKLGDFNLIAKTKTELEETQRELRKEEEAKGISWQR
RWFKDFDYSVTPEEGALVPEKDDTFLKLASALNLSTKNAPSGTLVGDKED
RKEDLSSIHWRFQRELWDEEKEIVL
3D structure
PDB4fes Synthesis and structure of 16,22-diketocholesterol bound to oxysterol-binding protein Osh4.
ChainB
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0T9 B F13 F42 Q96 Y97 E107 K109 N165 Q181 I203 F15 F44 Q98 Y99 E109 K111 N167 Q183 I205
Gene Ontology
Molecular Function
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0008142 oxysterol binding
GO:0008289 lipid binding
GO:0070273 phosphatidylinositol-4-phosphate binding
GO:0070300 phosphatidic acid binding
GO:0120015 sterol transfer activity
Biological Process
GO:0006665 sphingolipid metabolic process
GO:0006869 lipid transport
GO:0006887 exocytosis
GO:0006892 post-Golgi vesicle-mediated transport
GO:0006897 endocytosis
GO:0015918 sterol transport
GO:0030011 maintenance of cell polarity
GO:0034727 piecemeal microautophagy of the nucleus
GO:0035621 ER to Golgi ceramide transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4fes, PDBe:4fes, PDBj:4fes
PDBsum4fes
PubMed23756172
UniProtP35844|KES1_YEAST Oxysterol-binding protein homolog 4 (Gene Name=KES1)

[Back to BioLiP]