Structure of PDB 4fcm Chain B

Receptor sequence
>4fcmB (length=135) Species: 9606 (Homo sapiens) [Search protein sequence]
MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDKPAD
AVYGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQ
ALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVF
3D structure
PDB4fcm Crystal Structures of the Human G3BP1 NTF2-Like Domain Visualize FxFG Nup Repeat Specificity.
ChainB
Resolution2.69 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B P6 V11 E14 F15 Q18 R32 F33 E117 K123 F124 Y125 P6 V11 E14 F15 Q18 R32 F33 E114 K120 F121 Y122
External links
PDB RCSB:4fcm, PDBe:4fcm, PDBj:4fcm
PDBsum4fcm
PubMed24324649
UniProtQ13283|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (Gene Name=G3BP1)

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