Structure of PDB 4fbq Chain B

Receptor sequence
>4fbqB (length=402) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
AFEENRRLRNLGSVEYIENTIRILISSDPHVGYGEKDPVRGNDSFVSFNE
ILEIARERDVDMILLGGDIFHDNKPSRKALYQALRSLRLNCLGDKPCELE
LLSAVCNINYLDPNINVAIPVFSIHGNHDDGRYSALDILQVTGLVNYFGR
VPENDNIVVSPILLQKGFTKLALYGISNVRDERLYHSFRENKVKFLRPDL
YRDEWFNLLTVHQNHSAHTPTSYLPESFIQDFYDFVLWGHEHECLIDGSY
NPTQKFTVVQPGSTIATSLSPGETAPKHCGILNITGKDFHLEKIRLRTVR
PFIMKDIILSEVSSIPPMVENKKEVLTYLISKVEEAITEANAQWYEAQGT
VPVVENEKPPLPLIRLRVDYTGGYQTENPQRFSNRFVGRVANATDVVQFY
LK
3D structure
PDB4fbq Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B D1025 H1027 D1065 H1252 D28 H30 D68 H242
BS02 MN B D1065 N1133 H1222 H1250 D68 N127 H212 H240
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0008296 3'-5'-DNA exonuclease activity
GO:0016787 hydrolase activity
GO:0030145 manganese ion binding
Biological Process
GO:0006302 double-strand break repair
Cellular Component
GO:0005634 nucleus
GO:0030870 Mre11 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4fbq, PDBe:4fbq, PDBj:4fbq
PDBsum4fbq
PubMed22705791
UniProtO43070|NBS1_SCHPO DNA repair and telomere maintenance protein nbs1 (Gene Name=nbs1);
Q09683|RAD32_SCHPO Double-strand break repair protein rad32 (Gene Name=rad32)

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