Structure of PDB 4fbc Chain B

Receptor sequence
>4fbcB (length=278) Species: 4513 (Hordeum vulgare) [Search protein sequence]
KMAKNVDKPLFTATFNVQASSADYATFIAGIRNKLRNPAHFSHNRPVLPP
VEPNVPPSRWFHVVLKASPTSAGLTLAIRADNIYLEGFKSSDGTWWELTP
GLIPGATYVGFGGTYRDLLGDTDKLTNVALGRQQLADAVTALHGRTKADK
PSGPKQQQAREAVTTLLLMVNEATRFQTVSGFVAGLLHPKAVAAASGKIG
NEMKAQVNGWQDLSAALLKTDVKPPPGKSPAKFAPIEKMGVRTAVQAANT
LGILLFVEVPGGLTVAKALELFHASGGK
3D structure
PDB4fbc Structures of the ribosome-inactivating protein from barley seeds reveal a unique activation mechanism.
ChainB
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.22: rRNA N-glycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP B Y87 L88 L170 R178 Y84 L85 L167 R175
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0030598 rRNA N-glycosylase activity
GO:0090729 toxin activity
Biological Process
GO:0017148 negative regulation of translation
GO:0031640 killing of cells of another organism
GO:0035821 modulation of process of another organism
GO:0050832 defense response to fungus
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4fbc, PDBe:4fbc, PDBj:4fbc
PDBsum4fbc
PubMed23090398
UniProtP22244|RIP1_HORVU Protein synthesis inhibitor I (Gene Name=RIP30)

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