Structure of PDB 4f4z Chain B

Receptor sequence
>4f4zB (length=341) Species: 273057,330779 [Search protein sequence]
MIVLFVDFDYFYAQVEEVLNPSLKGKPVVVCVFSGRFEDSGAVATANYEA
RKFGVKAGIPIVEAKKILPNAVYLPMRKEVYQQVSSRIMNLLREYSEKIE
IASIDEAYLDISDKVRDYREAYNLGLEIKNKILEKEKITVTVGISKNKVF
AKIAADMAKPNGIKVIDDEEVKRLIRELDIADVPGIGNITAEKLKKLGIN
KLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVRKSIGRYLT
LPYNTRDVKVILPYLKKAINEAYNKVNGIPMRITVIAIMEDLDILSKGKK
FKHGISIDNAYKVAEDLLRELLVRDKRRNVRRIGVKLDNII
3D structure
PDB4f4z Y-family polymerase conformation is a major determinant of fidelity and translesion specificity.
ChainB
Resolution2.305 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B A57 G58 G185 I186 G187 I189 T190 K297 K300 R324 A57 G58 G185 I186 G187 I189 T190 K297 K300 R324
BS02 dna B A42 G58 A220 K221 S244 Y248 R332 A42 G58 A220 K221 S244 Y248 R332
BS03 CA B D7 E106 D7 E106
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:4f4z, PDBe:4f4z, PDBj:4f4z
PDBsum4f4z
PubMed23245850
UniProtQ4JB80|DPO4_SULAC DNA polymerase IV (Gene Name=dbh);
Q97W02|DPO4_SACS2 DNA polymerase IV (Gene Name=dbh)

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