Structure of PDB 4f38 Chain B

Receptor sequence
>4f38B (length=192) Species: 10090 (Mus musculus) [Search protein sequence]
TAEQLAQIAAENVNYKPPAQKSIQEIQELDKDDESLRKYKEALLGRVAVS
ADPNVPNVVVTRLTLVCSTAPGPLELDLTGDLESFKKQSFVLKEGVEYRI
KISFRVNREIVSGMKYIQHTYRKGVKIDKTDYMVGSYGPRAEEYEFLTPM
EEAPKGMLARGSYNIKSRFTDDDRTDHLSWEWNLTIKKEWKD
3D structure
PDB4f38 Quantitative Analysis of Prenylated RhoA Interaction with Its Chaperone, RhoGDI.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GER B L75 Y110 Q130 I139 D140 P166 W194 L63 Y98 Q118 I127 D128 P154 W182
Gene Ontology
Molecular Function
GO:0005094 Rho GDP-dissociation inhibitor activity
GO:0005096 GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0007266 Rho protein signal transduction
GO:0032880 regulation of protein localization
GO:0035023 regulation of Rho protein signal transduction
GO:0071526 semaphorin-plexin signaling pathway
GO:0098693 regulation of synaptic vesicle cycle
Cellular Component
GO:0001772 immunological synapse
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0098685 Schaffer collateral - CA1 synapse

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Cellular Component
External links
PDB RCSB:4f38, PDBe:4f38, PDBj:4f38
PDBsum4f38
PubMed22628549
UniProtQ99PT1|GDIR1_MOUSE Rho GDP-dissociation inhibitor 1 (Gene Name=Arhgdia)

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