Structure of PDB 4ezc Chain B

Receptor sequence
>4ezcB (length=346) Species: 9913 (Bos taurus) [Search protein sequence]
GYITGDMKEFANWLKDKPQALQFVDWVLRGISQVVFVSNPISGILILVGL
LVQNPWCALNGCVGTVVSTLTALLLSQDRSAITAGLQGYNATLVGILMAI
YSDKGNYFWWLLFPVSAMSMTCPVFSSALNSVLSKWDLPVFTLPFNMALS
MYLSATGHYNPFFPSTLITPVTSVPNVTWPDLSALQLLKSLPVGVGQIYG
CDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIIAGLSLSAPFEDIYAGL
WGFNSSLACIAIGGTFMALTWQTHLLALACALFTAYLGASMSHVMAVVGL
PSGTWPFCLATLLFLLLTTKNPNIYKMPISKVTYPEENRIFYLQSR
3D structure
PDB4ezc Structure and permeation mechanism of a mammalian urea transporter.
ChainB
Resolution2.36 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SPL B S320 V324 L339 S290 V294 L309
BS02 BGC B Y137 F138 W139 W140 Y107 F108 W109 W110
BS03 SPL B M181 W335 M151 W305
Gene Ontology
Molecular Function
GO:0015204 urea transmembrane transporter activity
GO:0015265 urea channel activity
Biological Process
GO:0071918 urea transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016323 basolateral plasma membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4ezc, PDBe:4ezc, PDBj:4ezc
PDBsum4ezc
PubMed22733730
UniProtQ5QF96|UT1_BOVIN Urea transporter 1 (Gene Name=SLC14A1)

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