Structure of PDB 4ewz Chain B
Receptor sequence
>4ewzB (length=30) Species:
9606
(Homo sapiens) [
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FVNQHLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB
4ewz
Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Chain
B
Resolution
1.791 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
B
F1 N3 Q4 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 P28 T30
F1 N3 Q4 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 P28 T30
Gene Ontology
Molecular Function
GO:0005179
hormone activity
Cellular Component
GO:0005576
extracellular region
View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB
RCSB:4ewz
,
PDBe:4ewz
,
PDBj:4ewz
PDBsum
4ewz
PubMed
23692694
UniProt
P01308
|INS_HUMAN Insulin (Gene Name=INS)
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