Structure of PDB 4ewx Chain B

Receptor sequence
>4ewxB (length=30) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB4ewx Structural meta-analysis of regular human insulin in pharmaceutical formulations.
ChainB
Resolution2.201 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B F1 N3 Q4 H5 L6 C7 L11 L15 C19 R22 G23 F24 F25 P28 T30 F1 N3 Q4 H5 L6 C7 L11 L15 C19 R22 G23 F24 F25 P28 T30
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:4ewx, PDBe:4ewx, PDBj:4ewx
PDBsum4ewx
PubMed23692694
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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