Structure of PDB 4euc Chain B

Receptor sequence
>4eucB (length=504) Species: 435 (Acetobacter aceti) [Search protein sequence]
TERIRNVALRSKVCPAETASELIKHGDVVGTSGFTGAGYPKEVPKALAQR
MEAAHDRGEKYQISLITGASTGPQLDGELAKANGVYFRSPFNTDATMRNR
INAGETEYFDNHLGQVAGRAVQGNYGKFNIALVEATAITEDGGIVPTSSV
GNSQTFLNLAEKVIIEVNEWQNPMLEGIHDIWDGNVSGVPTRDIVPIVRA
DQRVGGPVLRVNPDKIAAIVRTNDRDRNAPFAAPDETAKAIAGYLLDFFG
HEVKQNRLPPSLLPLQSGVGNVANAVLEGLKEGPFENLVGYSAVIQDGML
AMLDSGRMRIASASSFSLSPEAAEEINNRMDFFRSKIILRQQDVSNSPGI
IRRLGCIAMNGMIEADIYGNVNSTRVMGSKMMNGIGGSGDFARSSYLSIF
LSPSTAKGGKISAIVPMAAHVDHIMQDAQIFVTEQGLADLRGLSPVQRAR
EIISKCAHPDYRPMLQDYFDRALKNSFGKHTPHLLTEALSWHQRFIDTGT
MLPS
3D structure
PDB4euc Crystal Structures of Acetobacter aceti Succinyl-Coenzyme A (CoA):Acetate CoA-Transferase Reveal Specificity Determinants and Illustrate the Mechanism Used by Class I CoA-Transferases.
ChainB
Resolution2.644 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.3.18: succinyl-CoA:acetate CoA-transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0RQ B G269 V270 G271 N272 V273 N361 M363 I364 M383 N384 G385 G387 G388 S389 A407 K408 I412 G268 V269 G270 N271 V272 N360 M362 I363 M382 N383 G384 G386 G387 S388 A406 K407 I411 PDBbind-CN: -logKd/Ki=6.10,Kd=0.8uM
Gene Ontology
Molecular Function
GO:0003986 acetyl-CoA hydrolase activity
GO:0008410 CoA-transferase activity
GO:0008775 acetate CoA-transferase activity
GO:0016740 transferase activity
Biological Process
GO:0006083 acetate metabolic process
GO:0006084 acetyl-CoA metabolic process
GO:0006085 acetyl-CoA biosynthetic process
GO:0019427 acetyl-CoA biosynthetic process from acetate
GO:0045733 acetate catabolic process
GO:1901289 succinyl-CoA catabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4euc, PDBe:4euc, PDBj:4euc
PDBsum4euc
PubMed23030530
UniProtB3EY95|SCACT_ACEAC Succinyl-CoA:acetate CoA-transferase

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