Structure of PDB 4eu7 Chain B

Receptor sequence
>4eu7B (length=504) Species: 435 (Acetobacter aceti) [Search protein sequence]
TERIRNVALRSKVCPAETASELIKHGDVVGTSGFTGAGYPKEVPKALAQR
MEAAHDRGEKYQISLITGASTGPQLDGELAKANGVYFRSPFNTDATMRNR
INAGETEYFDNHLGQVAGRAVQGNYGKFNIALVEATAITEDGGIVPTSSV
GNSQTFLNLAEKVIIEVNEWQNPMLEGIHDIWDGNVSGVPTRDIVPIVRA
DQRVGGPVLRVNPDKIAAIVRTNDRDRNAPFAAPDETAKAIAGYLLDFFG
HEVKQNRLPPSLLPLQSGVGNVANAVLEGLKEGPFENLVGYSEVIQDGML
AMLDSGRMRIASASSFSLSPEAAEEINNRMDFFRSKIILRQQDVSNSPGI
IRRLGCIAMNGMIEADIYGNVNSTRVMGSKMMNGIGGSGDFARSSYLSIF
LSPSTAKGGKISAIVPMAAHVDHIMQDAQIFVTEQGLADLRGLSPVQRAR
EIISKCAHPDYRPMLQDYFDRALKNSFGKHTPHLLTEALSWHQRFIDTGT
MLPS
3D structure
PDB4eu7 Crystal Structures of Acetobacter aceti Succinyl-Coenzyme A (CoA):Acetate CoA-Transferase Reveal Specificity Determinants and Illustrate the Mechanism Used by Class I CoA-Transferases.
ChainB
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.3.18: succinyl-CoA:acetate CoA-transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA B N361 M363 I364 N384 G385 S389 A407 K408 I412 N360 M362 I363 N383 G384 S388 A406 K407 I411
BS02 CIT B T36 S71 T94 R228 P231 T35 S70 T93 R227 P230 MOAD: Ki=150mM
Gene Ontology
Molecular Function
GO:0003986 acetyl-CoA hydrolase activity
GO:0008410 CoA-transferase activity
GO:0008775 acetate CoA-transferase activity
GO:0016740 transferase activity
Biological Process
GO:0006083 acetate metabolic process
GO:0006084 acetyl-CoA metabolic process
GO:0006085 acetyl-CoA biosynthetic process
GO:0019427 acetyl-CoA biosynthetic process from acetate
GO:0045733 acetate catabolic process
GO:1901289 succinyl-CoA catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4eu7, PDBe:4eu7, PDBj:4eu7
PDBsum4eu7
PubMed23030530
UniProtB3EY95|SCACT_ACEAC Succinyl-CoA:acetate CoA-transferase

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