Structure of PDB 4eql Chain B

Receptor sequence
>4eqlB (length=479) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
ETFEKQLKDLTSNVKSIQDNLLEEIITPNTKTEYLQRFLIDRFDKELFKK
NVPIVSYEDIKPYLDRVVNGESSDVISARTITGFLLSSGTSGGAQKMMPW
NNKYLDNLTFIYDLRMQVITKHVKGVEEGKGMMFLFTKQESMTPSGLPAR
VATSSYFKSDYFKNRPSNWYYSYTSPDEVILCPNNTESLYCHLLCGLVQR
DEVVRTGSIFASVMVRAIEVLKNSWEELCSNIRSGHLSNWVTDLGCQNSV
SLVLGGPRPELADTIEEICNQNSWKGIVKRLWPNTKYIETVVTGSMGQYV
PMLNYYCNDLPLVSTTYGSSETTFGINLDPLCKPEDVSYTFMPNMSYFEF
IPMDGGDKNDVVDLEDVKLGCTYEPVVTNFAGLYRMRVGDIVLVTGFYNN
APQFKFVRRENVVLSIDSDKTNEETSYADTSTFPGHYVVYLLSTCCLVME
ESLDNVYKRCRFKDGSIGPLEIRAKFFSI
3D structure
PDB4eql Structural basis for prereceptor modulation of plant hormones by GH3 proteins.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AMP B S95 S96 V299 T301 T324 Y325 G326 S327 S328 Y347 D398 F414 R417 S87 S88 V291 T293 T316 Y317 G318 S319 S320 Y339 D390 F406 R409
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016874 ligase activity
GO:0052625 N-(4-aminobenzoyl)-L-glutamate synthetase activity
GO:0052626 N-benzoyl-L-glutamate synthetase activity
GO:0052627 N-vanillate-L-glutamate synthetase activity
GO:0052628 N-(4-hydroxybenzoyl)-L-glutamate synthetase activity
Biological Process
GO:0006952 defense response
GO:0009626 plant-type hypersensitive response
GO:0009863 salicylic acid mediated signaling pathway
GO:0010112 regulation of systemic acquired resistance
GO:0016046 detection of fungus
GO:0018874 benzoate metabolic process
GO:0034052 positive regulation of plant-type hypersensitive response
GO:0042742 defense response to bacterium
GO:0071456 cellular response to hypoxia

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Molecular Function

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Biological Process
External links
PDB RCSB:4eql, PDBe:4eql, PDBj:4eql
PDBsum4eql
PubMed22628555
UniProtQ9LYU4|GH312_ARATH 4-substituted benzoates-glutamate ligase GH3.12 (Gene Name=GH3.12)

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