Structure of PDB 4ep4 Chain B

Receptor sequence
>4ep4B (length=166) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MVVAGIDPGITHLGLGVVAVEGKGALKARLLHGEVVKTSPQEPAKERVGR
IHARVLEVLHRFRPEAVAVEEQFFYRQNELAYKVGWALGAVLVAAFEAGV
PVYAYGPMQVKQALAGHGHAAKEEVALMVRGILGLKEAPRPSHLADALAI
ALTHAFYARMGTAKPL
3D structure
PDB4ep4 Structural asymmetry in the Thermus thermophilus RuvC dimer suggests a basis for sequential strand cleavages during Holliday junction resolution.
ChainB
Resolution1.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.10: crossover junction endodeoxyribonuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B D7 H143 D7 H143
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0008821 crossover junction DNA endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination
Cellular Component
GO:0005737 cytoplasm
GO:0048476 Holliday junction resolvase complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4ep4, PDBe:4ep4, PDBj:4ep4
PDBsum4ep4
PubMed23118486
UniProtQ5SJC4|RUVC_THET8 Crossover junction endodeoxyribonuclease RuvC (Gene Name=ruvC)

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