Structure of PDB 4eoj Chain B

Receptor sequence
>4eojB (length=257) Species: 9606 (Homo sapiens) [Search protein sequence]
PDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEY
KLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEV
AEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPA
NCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPES
LIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLN
PPETLNL
3D structure
PDB4eoj An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity.
ChainB
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG B M200 Q203 I206 M25 Q28 I31
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

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Molecular Function

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Biological Process
External links
PDB RCSB:4eoj, PDBe:4eoj, PDBj:4eoj
PDBsum4eoj
PubMed22921070
UniProtP20248|CCNA2_HUMAN Cyclin-A2 (Gene Name=CCNA2)

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