Structure of PDB 4eme Chain B

Receptor sequence
>4emeB (length=473) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
YVDKKAREYAQDALKFIQRSGSNFLACKNLKERLENNGFINLSEGETWNL
NKNEGYVLCKENRNICGFFVGKNFNIDTGSILISIGHIDSCALKISPNNN
VIKKKIHQINVECYGSGLWHTWFDRSLGLSGQVLYKKGNKLVEKLIQINK
SVLFLPSLAIHLQNFSVKINYENHIKPIISTTLFNQLNKCINTDNSYPLL
YLLSKELNCKEEDILDFELCLMDTQEPCFTGVYEEFIEGARFDNLLGSFC
VFEGFIELVNSIKNHTSDNIHNNLYISIGYDHEEIGSLSEVGARSYCTKN
FIDRIISSVFKKEIHEKNLSVQEIYGNLVNRSFILNVDMAHCSHPNYPET
VQDNHQLFFHEGIAIKYNTNKNYVTSPLHASLIKRTFELYYNKYKQQIKY
QNFMVKNDTPCGSTVGSMVAANLSMPGIDIGIPQLAMHSIREIAAVHDVF
FLIKGVFAFYTYYNQVLSTCVHD
3D structure
PDB4eme X-ray crystal structure and specificity of the Plasmodium falciparum malaria aminopeptidase PfM18AAP.
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.11.21: aspartyl aminopeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B H87 D325 D435 H87 D243 D338
BS02 ZN B D325 E381 H535 D243 E284 H438
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
GO:0070006 metalloaminopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0043171 peptide catabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4eme, PDBe:4eme, PDBj:4eme
PDBsum4eme
PubMed22709581
UniProtQ8I2J3|DNPEP_PLAF7 Aspartyl aminopeptidase (Gene Name=M18AAP)

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