Structure of PDB 4ejy Chain B

Receptor sequence
>4ejyB (length=289) Species: 273068 (Caldanaerobacter subterraneus subsp. tengcongensis MB4) [Search protein sequence]
RMKYNVEEKGTKVIVRGIADFNLKETFESGQCFRWNEEEDGSYTGVAYDR
VVNVKLEGDTLIIDNTNLTDFYDIWFDYFDLGRDYGQIKESLSKDPVLKE
AIKFGQGIRILRQDTWETLVSFIVSQNNRIPQIKKVIENLATSFGNPIEY
KGKIYYTFPKPEELVMYDVETIAKTRCGFRAKYIFDAASKVFSGEINLLK
LHEYSTSEIRDILMTINGVGPKVADCVILYSIGRYDTFPTDVWIKRIVEH
LYLKREGTPVEIQLFAIDKFGDLSGFAQQYLFYYGREMG
3D structure
PDB4ejy Crystal structures of MBOgg1 in complex with two abasic DNA ligands
ChainB
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) K221 D240
Catalytic site (residue number reindexed from 1) K222 D241
Enzyme Commision number 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B Q125 N126 R128 F178 N216 G217 G219 P220 K221 V222 D240 V241 Q126 N127 R129 F179 N217 G218 G220 P221 K222 V223 D241 V242 PDBbind-CN: Kd=0.86nM
BS02 dna B N126 R175 G177 F178 R179 N127 R176 G178 F179 R180 PDBbind-CN: Kd=0.86nM
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003824 catalytic activity
GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity
GO:0140097 catalytic activity, acting on DNA
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair
GO:0006289 nucleotide-excision repair

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4ejy, PDBe:4ejy, PDBj:4ejy
PDBsum4ejy
PubMed23246782
UniProtQ8R5T9

[Back to BioLiP]