Structure of PDB 4e7s Chain B

Receptor sequence
>4e7sB (length=752) Species: 9823 (Sus scrofa) [Search protein sequence]
KPVWAPHPTDGFQVGNIVRRGPDSLTIEPLNQKGKTFLALINQVFPAEED
SKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIP
KIYSSETIKSYQGKSLGTMPPHVFAIADKAFRDMKVLKLSQSIIVSGESG
AGKTENTKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSS
RFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAG
ASEDIRERLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEYLKAG
SLKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEE
AGSTGCNLKNKSTQALEYCAELLGLDQDDLRVSLTTRKVPLKVEQANNAR
DALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQ
FCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEA
RLVGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLSIPRKSKLAIHEN
IRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIREL
FESFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQIL
SQLQCSGMVSVLDLMQGGFPSRASFHELYNMYKKYMPDKLARLDPRLFCK
ALFKALGLNEIDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNH
WL
3D structure
PDB4e7s Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin VI.
ChainB
Resolution2.25 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S153 G154 T158 N200 S203 S204 G459 E461
Catalytic site (residue number reindexed from 1) S149 G150 T154 N196 S199 S200 G439 E441
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B N98 P99 F101 G154 G156 K157 T158 E159 N200 N94 P95 F97 G150 G152 K153 T154 E155 N196
BS02 MG B T158 S204 T154 S200
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4e7s, PDBe:4e7s, PDBj:4e7s
PDBsum4e7s
PubMed22940248
UniProtF1RQI7

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